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A new strategy for improving the precision and accuracy of isotope ratio analysis by quadrupole ICP-MS with the optimization of ion beam trajectory

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00371K, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Xing Li, Haitao Li, Dingwen Zhang, Xin Yang, Yu Cui, Wei Guo, Lanlan Jin, Shenghong Hu
A new strategy is proposed to improve the accuracy and precision of isotope analysis using ICP-QMS by controlling ion motion trajectories and reducing mass discrimination.
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PolyA-tail-mediated assembly of a gold nanoparticle-based turn-on fluorescent aptasensor for ultrasensitive detection of perfluorooctanoic acid

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00236F, Communication
Zhuo-Ying Li, Li-Xia Yan, Xu Zhao, Hua Lin, Li-Jian Chen, Xiu-Ping Yan
A turn-on fluorescent aptasensor enables ultrasensitive PFOA detection via a polyA-aptamer anchored AuNP-based FRET strategy, validated in spiked fish samples.
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Development and validation of a cross-species breath metabolomics platform for translational VOC analysis

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00164E, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Zhiheng Yu, Yongyan Ji, Zijun Meng, Xiang Li
A validated cross-species breath metabolomics platform enables transferable VOC discovery from human studies to animal model verification.
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Digital image method based on a smartphone assisted by hydrophobic natural deep eutectic solvent for iron quantification in dietary supplements

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00456C, Paper
Gabriel Bercley de Lima Vitorino, Jackson Rodrigo dos Santos Silva, Vinícius de Alcântara Carvalho, João Paulo Barbosa de Almeida, Willian Toito Suarez, Severino Carlos Bezerra de Oliveira, Vagner Bezerra dos Santos
Extraction and detection of iron from supplementary materials using natural deep eutectic solvents and the digital image method.
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A magnetic separation-based dual-mode aptasensor integrating FRET fluorescence and UV absorption for early diagnosis of hepatocellular carcinoma

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00682E, Paper
Jianghua Wang, Jianfeng Tang
Early diagnosis of hepatocellular carcinoma (HCC) is crucial for improving patient survival; however, conventional detection methods using HepG2 cells (a typical HCC cell line) have inherent limitations.
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Syringe Pressure-Assisted Switchable Hydrophilicity Solvent Microextraction with Smartphone Digital Image Colorimetry: A Rapid Method for Trace Cobalt Determination

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00606J, Paper
Yingying Zhao, Yi Shi, Jiayi Hu, Fuchun Ji, Xin Liu, Huiqiong Huang, Zhengui Li, Shengchun Yang, Xiaodong Wen
Heavy metal pollution poses a major threat to global environment and public health. Current methods for detecting heavy metals require expensive instruments and laborious operations, calling for simple and rapid...
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Simple yet sensitive MicroRNA detection using allosteric probe-initiated triple amplification and Cas13a/crRNA-based amplification reaction

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00578K, Paper
He Chen, Chaonan Zhang
MicroRNAs (miRNAs) have emerged as promising biomarkers for early diagnosis and management of degenerative disc disease (DDD); however, their low abundance and high sequence homology pose significant challenges for clinical detection.
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Fluorescence sensor array integrated with machine learning: robust discrimination of multiple metal ions using carboxyl-rich carbon dots

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00272B, Paper
Yixiang Li, Weidong Zhang, Da Chen, Xiaobo Sun, Chun Li, Baomin Yang, Jinping Wang
Carboxyl-rich carbon dots combined with six chemically distinct pH 5.0 media generate orthogonal fluorescence fingerprints, enabling machine-learning-assisted discrimination of 15 metal ions and their mixtures in complex environmental samples.
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SERS-based detection of pesticide residues in food: substrate fabrication, optimization, and applications

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00408C, Critical Review
Yuhang Que, Ling Xin, Lingyao Zhu, Li Wang, Zhuang Li
This work reviews SERS substrate preparation and optimization strategies, and recent advances (2020-present) in SERS for pesticide residue detection in food, including principles, adaptation strategies, advantages, limitations, and solutions.
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A quinoxaline-based conjugated microporous polymer-coating for solid phase microextraction of polycyclic aromatic hydrocarbons in environmental samples

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00360E, Paper
Gang Xiang, Liushi Xu, Zheng Li, Fengping Liu, Huan Lian, Cuizhong Zhang, Jing Sun, Jinyun Peng, Yunyu Li
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants with severe ecological toxicity, released via both biogenic and anthropogenic pathways.
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