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Principal component analysis-assisted fluorescent phenylboronic acid probes for discrimination and detection of living pathogenic bacteria

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01421B, Paper

Fenying Wang, Shuqing Xiong, Jinjin Wang, Haoqi Jia, Kai Gao, Jianlin Li, Hua Guo, Qianjin Li
A bacteria discrimination platform can be simply constructed by integrating a phenylboronic acid-functionalized fluorescent probe with machine learning methods.
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Fluorescent biosensors for the detection of foodborne pathogenic bacteria in food: a comprehensive review

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01025J, Critical Review

Yuan Zhang, Yu Wu, Anjie Guo, Yuan Liu, Qing Sun, Xiaobo Zou, Zongbao Sun
Foodborne pathogenic bacterial contamination poses a major challenge to global food safety and public health, making the development of rapid, sensitive, and specific detection technologies critically important.
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Nanoscale mapping of nucleolin–aptamer interactions on lung cancer cells reveals binding affinity hierarchy and spatial heterogeneity

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01088H, Paper

Longyun Chen, Rongrong Feng, Qianhui Xu, Huaiwei Zhang, You Sun, Weijie Peng, Weidong Zhao, Feng Jiang
Atomic force microscopy probes nucleolin-aptamer interactions on lung cancer cells at single molecule resolution, measuring binding forces in piconewton and electrical properties with 0.1 mV sensitivity.
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Instant detection of goat leather artifacts using europium(III)-based fluorescent immunochromatographic assay strips

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01168J, Paper

Ruixue Sun, Chao Zhang, Lubin Hua, Xiaojing Kang, Lianpeng Lv, Hui Si, Yang Zhou, Hailiang Yang, Bing Wang
Leather artifacts represent a vital part of cultural heritage, embodying centuries of craftsmanship and artistic tradition.
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Early thalassemia screening via hemoglobin β-subunit detection: a portable PDA–PoPD-MWCNT electrochemical immunosensor

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01282A, Paper

Xuanxiu Da, Bolu Sun, Zixia Wang, Yuqiong Wu, Huajie Li, Miao Zhou, Ying Lv, Xinlan Wang, Haiying He, Jiali Kang, Chenyv Qin, Xiangdong Wang, Lin Yang, Xiuying Pu, Hai Wang
Schematic of the electrochemical immunosensor for the detection of the hemoglobin β subunit (HB-β).
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Rotating gold microwire electrode for the voltammetric detection of mercury and arsenic in shellfish

Anal. Methods, 2025, 17,8053-8060
DOI: 10.1039/D5AY01018G, Paper

Wesley J. McCormick, Eveline Düker, Matthew McCole, Christopher McEleney, Denis McCrudden
Monitoring mercury (Hg) and arsenic (As) in bivalve shellfish is crucial for ensuring food safety and protecting human health, given the bioaccumulation potential of these toxic contaminants.
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A dual ligand Eu-MOF with high stability and quantum yield for the detection of trace Fe3+, CrO42− and Cr2O72− in aqueous environments

Anal. Methods, 2025, 17,8029-8041
DOI: 10.1039/D5AY01329A, Paper

Nanhai Zhang, Deyan Liu, Rui Zhang, Qinghe Song, Guangjun He, Shixing Wang, Libo Zhang
A dual ligand Eu-MOF with high stability and quantum yield was synthesized for the efficient detection of trace Fe³⁺, CrO4²⁻ and Cr₂O7²⁻. The fluorescence sensing mechanism involved photoinduced electron transfer and competitive absorption.
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Application of azacyclobutane modified perylene imide fluorescent probes targeting lipid droplets in the diagnosis of metabolic dysfunction-associated fatty liver

Anal. Methods, 2025, 17,8023-8028
DOI: 10.1039/D5AY01145K, Paper

Lixia Zhang, Tingting Hao, Yongqing Wang, Lin Cai, Rui Huang, Hongmei Liu
Biological applications of probe PDIs-560.
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Effects of microscans on the results of orbitrap mass spectrometry analysis of natural organic matter

Anal. Methods, 2025, 17,7975-7984
DOI: 10.1039/D5AY01313E, Paper

Sophia M. Byvsheva, Mikhail A. Proskurnin, Dmitry S. Volkov
This study experimentally confirms that averaging individual spectral transients (microscans) is not equivalent to averaging scans. The influence of microscans number is significant and must be considered both during in-laboratory measurements.
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Establishment of a potential reference measurement procedure and reference material for PIK3CA H1047R mutation detection

Anal. Methods, 2025, 17,7910-7919
DOI: 10.1039/D5AY00429B, Paper

Shangjun Wang, Hongmei Ji, Yuqian Jia, Bei Huang, Haijiao Dong, Ziyue Liu, Zhuoying Xie, Jie Sun, Jiayi Qian, Zhongze Gu
A reference measurement procedure and a reference material for the PIK3CA H1047R mutation detection were established to enhance the accuracy and reliability of mutation testing results.
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