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A RP-HPLC-UV method for the dual detection of fluconazole and clobetasol propionate and application to a model dual drug delivery hydrogel

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D4AY02219J, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Robyn A. Macartney, Annabelle T. R. Fricker, Andrew M. Smith, Stefano Fedele, Ipsita Roy, Jonathan C. Knowles
A validated UV-HPLC method for the rapid detection of fluconazole and clobetasol propionate is presented. The method is proven to show excellent linearity for both drugs, alongside good robustness, specificity, precision, accuracy and selectivity.
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CRISPR/Cas12a-coupled multiplexed amplification system for ultrasensitive detection of miRNA-155

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY00415B, Paper

Zhengdong Ai, Wenjun Wang, Xiang Li, Xianfeng Wang, Jia Chen, Jianming Wu, Shiying Zhou
miRNA plays an important role in gene regulation and can be an effective biomarker for disease diagnosis. Herein, a new miRNA detection platform based on CRISPR/Cas12a-coupled multiplexed amplification system is...
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Eu-COF-based fluorescence and portable detection of acetone in exhaled breath

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY00230C, Paper

Zhe Jiao, Xiudong Shi, Xiaolin Zhang, Xiaofang Zhao, Yueting Wang, Feng Xu, Jing Zhang
Exhaled biomarker detection, as a non-invasive and portable analytical method, holds great potential in the field of point-of-care testing.
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Application of Microfluidic Modulation Spectroscopy for Simultaneous Structural and Thermal Stability Analysis of Commercial mAbs under Varying Formulation Conditions.

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D4AY02324B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yalan Yang, Chuanfei Yu, Maoqin Duan, Chunyu Liu, Meng Li, Gang Wu, Jialiang Du, Gangling Xu, Xiaojuan Yu, Lan Wang
The secondary structure of proteins is extremely important because it contains some of the most fundamental information about how a protein folds into its tertiary and quaternary structure. The most...
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Near-infrared spectroscopy: application in ensuring food quality and safety

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D4AY02039A, Critical Review

Yuxia Xu, Tianyu Kong, Yinfei Ma, Yan Zhao, Le Chu, Mingzhu Zheng
The systematically reviewed near-infrared spectroscopy theory, characteristic absorption bands of active components, and their applications in food analysis, while addressing current technical limitations and future development prospects.
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Sustainable synthesis of tunable emissive sulphur-doped CDs: a synergistic approach for metal ion sensing and antimicrobial applications

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY00180C, Paper

Sneha V. Koparde, Omkar S. Nille, Akanksha G. Kolekar, Radhika B. Jadhav, Arpita Pandey Tiwari, Samadhan P. Pawar, Govind B. Kolekar
Time responsive multi emitting S-CDs were developed using biomass precursors by simple carbonization techniques. The S-CDs have potential multifaceted applications in tunable emissive fluorescent probes, development of analytical techniques, biomedical applications and environmental remediation.
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Exceptional quenching properties of tetrazine-based organic frameworks for fluorescently labeled nucleic acids and their applications in sensing

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY00328H, Paper

Chenggang Liu, Yanfei Kang, Wenjiao Li, Cheng Yao, Chan Song
Covalent organic frameworks (COFs) have garnered significant attention due to their unique properties, such as high surface area, porosity, chemical stability, and sustainability, which enable a wide range of applications...
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Towards the Development of an Alternative Analysis Method to Determine Lead in Eyeliner Cosmetics

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY00389J, Paper

Catherine McMahon, Toni Barstis, Rae Bellows, Charles Henry
Previous research has shown that potentially toxic elements may be present in cosmetic products as impurities or for pigmentation and may be linked to adverse health effects. Yet in low-resource...
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Comparison of neutron activation analysis, X-ray fluorescence spectrometry and inductively-coupled plasma mass spectrometry for the determination of rare earth element concentrations in Jordanian monazite ore

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY00436E, Paper

Ahmad Alsabbagh, Kamal Harahshah, Kafa Al-Khasawneh, Elizabeth J. New
Jordanian monazite ore, rich in REEs, undergoes wet gravity separation. XRF, ICP-MS, and INAA analyses reveal REE concentrations, ensuring precise assessment for effective extraction and application.
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Investigation of the interface structure and filler network formation of liquid silicone rubber/silica nanocomposites based on ATR-FTIR spectroscopy and chemometrics

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY00376H, Paper

Yuying Li, Qiuyu Long, Jia Luo, Chunhua Zhu, Yu Liu
This study uses ATR-FTIR and chemometrics to analyze silicone/silica nanocomposite interface during extraction. PCA reveals spectral shifts clarifying bound rubber and filler network development.
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