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Microfluidic-electrochemical sweat patches for athletes: monitoring lactate, electrolytes, and hydration status

Anal. Methods, 2026, 18,4970-4982
DOI: 10.1039/D6AY00936K, Minireview

Huibo Liu, Wanlei Lin
Microfluidic-electrochemical sweat patches enable real-time athletic monitoring by integrating lactate/electrolyte sensing, sweat handling, scalable fabrication, validation, and data analytics for personalized performance and hydration management.
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Development and validation of LC-MS/MS methods for the quantification of TMS-007, a member of the SMTP congeners, in rat plasma and brain: application to a preclinical pharmacokinetic study

Anal. Methods, 2026, 18,5125-5132
DOI: 10.1039/D6AY00057F, Paper

Yuanbin Hao, Yan Zhang, Huaye Gao, Chenjun Wu, Li Sun, Siqi Zhao, Shaofei Xie, Rong Chen
TMS-007 is a member of the SMTP congeners for the treatment of acute ischemic stroke. LC-MS/MS methods to quantify TMS-007 in various rat matrices were developed. The validated methods were applied to a preclinical study in a tMCAO rat model.
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Portable voltammetric determination of acetaminophen using DropSens-based screen-printed carbon electrodes for clinical and pharmaceutical applications

Anal. Methods, 2026, 18,5074-5085
DOI: 10.1039/D6AY00692B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Rocío Navarro-Utiel, Ana Ballester-Caudet, Sergio Cortés-Bautista, Pilar Campíns-Falcó
The increasing demand for portable, low-cost, and sustainable analytical methodologies has motivated the development of miniaturized electrochemical systems for pharmaceutical and clinical monitoring.
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Single-precursor-derived carbon and nitrogen co-doped CuO nanozymes for colorimetric detection of tetracycline

Anal. Methods, 2026, 18,5133-5140
DOI: 10.1039/D6AY00592F, Paper

Yu Liu, Jingjing Fang, Liangxiao Jiang, Hengchao Yang, Cheng Yao, Chan Song
The carbon and nitrogen co-doped CuO with high peroxidase-like catalytic activity was constructed via direct pyrolysis of copper(II) phthalocyanine (CuPc) as a single source precursor.
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Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

Anal. Methods, 2026, 18,5034-5040
DOI: 10.1039/D6AY00867D, Paper

Qingliang Lin, Yibin Zeng, Zhichao Yu, Dianping Tang, Xuejing Wu
This work designed a paper-based portable colorimetric immunoassay of carcinoembryonic antigen using strain-induced PtCu bimetallic nanozymes with smartphone readout.
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A rapid, multiplex, one-pot CRISPR/Dx system for visual detection of influenza A, influenza B, and respiratory syncytial viruses

Anal. Methods, 2026, 18,5052-5060
DOI: 10.1039/D6AY00425C, Paper

Qiyuan Xia, Rui Guo, Jianrong Xiao, Lu Zeng, Yumei Huang, Jiahui Li, Xiaoqing Chen, Tingting Huang, Bing Xiao, Chenyu Miao, Weihuang Liu, Qing-Le Liang, Cia-Hin Lau, Haibao Zhu
Multiplex detection of influenza A virus (IAV), influenza B virus (IBV), and respiratory syncytial virus (RSV) with one-pot RT-RPA-CRISPR/Cas12a system.
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A novel bubble rupture sensing methodology for sweat-driven disease diagnostics

Anal. Methods, 2026, 18,5105-5115
DOI: 10.1039/D6AY00583G, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Akshay Ajit Parmar, Anoop Kanjirakat, Dolfred Vijay Fernandes, Naresh Kumar Mani
The ionic strength of sweat fluid influences the bubble bursting time.
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Synthesis route attribution of highly toxic ethyl sesquimustard based on non-targeted screening strategy and GC-HRMS

Anal. Methods, 2026, 18,5141-5149
DOI: 10.1039/D6AY00005C, Paper

Yiming Tian, Yixin Gu, Jianfeng Wu, Jia Chen, Jinqiao Jiang, Yulong Liu, Wei You, Kaikai Li, Jianwei Xie
Synthesis route attribution enables accurate source tracing of Q and effective discrimination between distinct synthetic pathways.
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Advancements in plant-based materials for sustainable biomedical applications

Anal. Methods, 2026, 18,5013-5024
DOI: 10.1039/D5AY02086G, Critical Review

Meenakshi Choudhary, Dharmesh Kumar, Penny P. Govender, Sudheesh K. Shukla
Biosensing technologies play a critical role across the healthcare, environmental monitoring, and food safety sectors.
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Automated SPE-GC-MS/MS method for the biomonitoring of eight N-nitrosamines in human urine

Anal. Methods, 2026, 18,5041-5051
DOI: 10.1039/D6AY00432F, Paper

Wanjun Zhang, Run Zhou, Xiangyu Wang, Chao Yang, Chunhua Huang, Xinliang Ding
A highly automated SPE-GC-MS/MS workflow was developed for sensitive biomonitoring of eight N-nitrosamines in human urine using only 4 mL of sample.
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