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Metabolomics-based study of potential biomarkers and metabolic pathways in sepsis-associated acute kidney injury

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D5AY01405K, Paper
Xinyi Sun, Fang Li, Gaoyin Yang, Yuxin Wu, Jing Wang, Junhong Yang, Jiatong Li, Huanqin Wang, Shu Wang
Untargeted metabolomics identifies phenylethanolamine and tyramine as potential biomarkers for sepsis-associated acute kidney injury (SA‑AKI). Elevated levels of these metabolites are linked to disrupted phenylalanine, tyrosine and tryptophan biosynthesis pathways.
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A quinoxaline-based conjugated microporous polymer-coating for solid phase microextraction of polycyclic aromatic hydrocarbons in environmental sample

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00360E, Paper
Gang Xiang, Liushi Xu, Zheng Li, Fengping Liu, Huan Lian, Cuizhong Zhang, Jing Sun, Jinyun Peng, Yunyu Li
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants with severe ecological toxicity, released via both biogenic and anthropogenic pathways. Ultra-sensitive analytical methods for the quantitative monitoring of trace PAHs in...
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Analytical Strategies for Multi-Omics Profiling of Exercise-Induced Muscle Damage and Recovery: From Sampling and Separations to Chemometric Biomarker Discovery

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00150E, Minireview
Liufeng Shi, Lingyi Wei, Le Xu, Yongrui Tang
Exercise-induced muscle damage (EIMD) triggers a coordinated cascade of molecular responses that drive tissue repair and physiological adaptation. Recent advances in analytical chemistry have enabled multi-omics profiling to capture these...
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Development and validation of a cross-species breath metabolomics platform for translational VOC analysis

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00164E, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Xiang Li, Zhiheng Yu, Yongyan Ji, Zijun Meng
The lack of universal cross-species sampling and quality control methods has limited the potential of breath metabolomics to advance from clinical discovery to mechanistic validation. To address this challenge, this...
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An Al3+ ions-responsive blue emitting ionic liquid-based nano-optode and its implications for the detection of 2, 4, 6-trinitrophenol

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00179C, Paper
Shubham Lama, Sudhir Kumar Das
A blue-emitting ionic liquid, HNMIL, and its nanomaterial, nHNMIL, have been introduced for the cascade detection of Al3+ ions and nitroaromatic compounds (NACs), with detection and quantification limits in the nanomolar range.
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Ratiometric fluorescence determination of Gd(III) using plumbagin: method validation and analysis of real samples

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00311G, Paper
Do Tam Nhan, Le Thi Thanh Tran, Nguyen Le Anh, Pham Van Tat, Le Van Tan
In this study, the spectroscopic interaction between plumbagin (PLB) and Gd(III) was studied using UV-vis and fluorescence spectroscopy techniques.
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Species identification of animal glue adhesives on polychrome cultural heritage: an integrated analytical approach combining gel sampling, ATR-FTIR spectroscopy, and machine learning

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00017G, Technical Note
Xinyu Xie, Wanru Wang, Qin Huang, Wenyuan Zhang, Xinyue Zhu, Xiaoyan Liu, Haixia Zhang
Schematic of the integrated workflow for species identification of animal glue adhesives, including hydrogel sampling, ATR-FTIR analysis, and supervised machine learning classification.
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Rapid quantification of oxidation indicators in fish oil by digital image colourimetry

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D5AY02138C, Paper
Xianggang Yin, Xiaohan Zhao, Xin Chen, Jiayi Jiang, Lele Li, Qinting Jiang, Linlin Wu, Yifeng Zhou, Jun Huang
Smartphone-based digital image colourimetry rapidly determines the acid, peroxide and iodine values of fish oils for low-cost on-site monitoring and routine quality control.
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Acetonitrile-driven interface force field reconstruction of HLB-SPME: insight into the pesticide adsorption mechanism based on energy lattice point models

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00203J, Paper
Shuang Lei, Lulu Pu, Xinrong Chen, Chaoxuan Liao, Yanping Fu, Jiahao Xu, Yi Gao, Mengran Wang, Zhoubing Huang, Dali Sun
Acetonitrile reshapes the solid–liquid interface via four synergistic effects: interfacial polarity regulation, microheterogeneous structure construction, interfacial enrichment, and diffusion pathway optimization.
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An image-based food quality analysis framework driven by large language models

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00214E, Paper
Xiao-Yue Yin, Hai-Long Wu, Luo-Yuan Han, Ye He, Xiao-Zhi Wang, Tong Wang, Ru-Qin Yu
LLM-based visual inspection framework with two paths: text-only inference and vision-language inference. A lightweight GUI enables one-click automation. Models are evaluated on ripeness, freshness, and authenticity tasks.
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