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Reaction-induced fluorogenic sensing of benzodiazepines: a 3D-printed smartphone-based device with multivariate RGB optimization

Anal. Methods, 2026, 18,4839-4850
DOI: 10.1039/D6AY00325G, Paper

Thiago Alvares Zamaro de Freitas, Matheus Martins Guedes, Camilla Fonseca Silva, Marcella Matos Cordeiro Borges, Álvaro Cunha Neto, Josefredo Rodriguez Pliego, Cleocir José Dalmaschio, Keyller Bastos Borges
A portable 3D-printed smartphone fluorimetric platform enables benzodiazepine detection with multivariate RGB optimization (MLR: R² = 0.9998), achieving laboratory-grade analytical performance with field-deployable simplicity.
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A pathogen-activated DNAzyme triggers hybridization chain reaction for ultra-sensitive salivary detection of Helicobacter pylori

Anal. Methods, 2026, 18,4795-4804
DOI: 10.1039/D6AY00648E, Paper

Qiming Chen, Quanling Dong, Zhengrong Lu, Zhanmin Liu
Helicobacter pylori infection is a major etiological factor in chronic gastritis, peptic ulcer disease, and gastric cancer, highlighting the demand for sensitive, non-invasive, and operationally simple diagnostic strategies.
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A CHEF-driven fluorescent turn-on probe for sensitive and rapid Al3+ detection in live MDA-MB-231 cells

Anal. Methods, 2026, 18,4858-4865
DOI: 10.1039/D6AY00264A, Paper

Rahul Naskar, Gita Rani Murmu, Subrata Mandal, Rimi Mukherjee, Arpan Halder, Amitav Biswas, Moumita Ghosh, Saswati Gharami, Nabendu Murmu, Tapan K. Mondal
A novel fluorescent switch (PIMB) has been fabricated through a straightforward Schiff base reaction and exhibits highly selective sensing of Al³⁺ over other metal ions at physiological pH.
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Determination of short-chain chlorinated paraffins in carpets by gas chromatography-electron capture negative ionization mass spectrometry

Anal. Methods, 2026, 18,4950-4957
DOI: 10.1039/D6AY00647G, Paper

Ting Gu, Yongli Wu, Lianrui Mei, Yu Zhang, Yi Han
A method based on GC-ECNI-MS was developed for determining short-chain chlorinated paraffins (SCCPs) in carpets, offering data support for global risk control of SCCPs use in carpet products.
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Sweat-based electrochemical wearable biosensors for sports performance and fatigue monitoring: from laboratory prototypes to field deployment

Anal. Methods, 2026, 18,4753-4785
DOI: 10.1039/D6AY00459H, Tutorial Review

Umapathi Krishnamoorthy
Emerging sweat-based wearable biosensors offer non-invasive, continuous assessment of athlete performance, with innovations in sensing, data analytics, and system integration enabling practical deployment beyond laboratory settings.
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Development of a bioluminescent enzyme immunoassay for glycocholic acid based on a single-chain variable fragment-nanoluciferase fusion

Anal. Methods, 2026, 18,4819-4825
DOI: 10.1039/D6AY00731G, Paper

Yunping Mu, Huajian Cai, Xindan Zhang, Mingxia Lin, Junhao Zeng, Yiyun Wang, Ziming Wu, Suqing Zhao, Xiping Cui
As glycocholic acid (GCA) has been recognized as a biomarker for hepatocellular carcinoma (HCC), its detection is crucial for the prevention, diagnosis, and treatment of HCC.
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Stabilization of a ring-opened rhodamine probe via multi-noncovalent interactions for the dual-mode detection of nitazenes

Anal. Methods, 2026, 18,4876-4886
DOI: 10.1039/D6AY00429F, Paper

Yujie Feng, Yudong Li, Bingbing Zhao, Chuanfang Zhao, Jingxiang Li, Luyan Yang, Baiyi Zu, Xincun Dou
Nitazene opioids, representing a potent class of emerging synthetic substances, have emerged as a significant threat to public health and biosafety worldwide.
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Rational design of L-histidine-stabilized fluorescent copper nanoclusters for highly selective and sensitive detection of sunset yellow

Anal. Methods, 2026, 18,4826-4838
DOI: 10.1039/D6AY00800C, Paper

Xingwu Li, Xiaotian Liu, Lili Yuan, Zhengshan Tian
The water-soluble, blue-green fluorescent copper nanoclusters demonstrate exceptional stability in high-temperature and high-salt environments, overcoming the limitations of many fluorescent probes in complex matrices.
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Pheromone measurement using secondary electrospray ionization and portable membrane inlet mass spectrometry

Anal. Methods, 2026, 18,4786-4794
DOI: 10.1039/D6AY00269B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Stamatios Giannoukos, Dimitris Raptopoulos, Maria Konstantopoulou
A secondary electrospray ionization high-resolution mass spectrometry system and a portable membrane inlet mass spectrometer have been used for the first time to detect and monitor insect sex pheromones, both qualitatively and quantitatively.
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Sensitive and reliable Kawasaki disease related microRNA analysis via self-priming chain extension cascades

Anal. Methods, 2026, 18,4898-4906
DOI: 10.1039/D6AY00576D, Paper

Qiuling Huang, Jia Yang
Kawasaki disease (KD) is a leading cause of acquired heart disease in children, requiring timely diagnosis.
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