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Transwell-based analysis uncovers stimulus-specific chemotactic migration in Dictyostelium discoideum

Anal. Methods, 2026, 18,2838-2842
DOI: 10.1039/D6AY00051G, Communication
Miranda Bravo, Antonia Ramos-Guzmán, Diego Rojas, Ian Pérez, Andrés E. Marcoleta, Francisco P. Chávez
We report an adapted Transwell® assay for robust and quantitative analysis of chemotactic migration in Dictyostelium discoideum.
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Self-powered PEC/EC dual-mode sensing platform for sensitive TNF-α detection based on multifunctional mesoporous silica nanospheres

Anal. Methods, 2026, 18,2864-2871
DOI: 10.1039/D6AY00126B, Paper
Jing Feng, Huanhuan He, Luna Guo, Weiling Song, Hong Zhou
A multifunctional mesoporous silica nanosphere driven self-powered photoelectrochemical/electrochemical dual-mode platform for sensitive TNF-α detection.
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Rapid in situ analysis of tobacco chemical composition via ultrasonic nebulization extraction coupled with atmospheric pressure photoionization mass spectrometry

Anal. Methods, 2026, 18,2853-2863
DOI: 10.1039/D5AY01923K, Paper
Bing Qian, Yonghua Hu, Qiong Wu, Hongxing Li, Chulian Su, Chengyuan Liu, Yang Pan, Bingjun Han
A rapid in situ analytical method combining ultrasonic nebulization extraction and atmospheric pressure photoionization mass spectrometry allows direct analysis of endogenous components in complex tobacco matrices.
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Unraveling the Alteration of Chemical Compositions in Cordyceps and Its Host Larvae Using Mass Spectrometry Imaging

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00457A, Paper
Shipeng Sun, Yuchen Zou, Weiwei Tang, Zhengming Qian, Bin Li
Cordyceps (Chinese Caterpillar Fungus) is a precious medicinal and edible fungus-larvae complex that is naturally formed in a specific environment. However, limited data have been reported on spatial alterations in...
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Metabolomics-based study of potential biomarkers and metabolic pathways in sepsis-associated acute kidney injury

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D5AY01405K, Paper
Xinyi Sun, Fang Li, Gaoyin Yang, Yuxin Wu, Jing Wang, Junhong Yang, Jiatong Li, Huanqin Wang, Shu Wang
Abstract: Objective: One of the most frequent consequence of sepsis is sepsis-associated acute kidney injury (SA-AKI), which increases hospitalization and mortality risk. A qualitative and quantitative analysis of the metabolic...
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Unsupervised and Supervised Methodologies for Identification of Sample Pixels in Fourier Transform InfraRed Microspectroscopic Images

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D5AY02095F, Paper
Xiangyu Zhao, Yudong Tian, Jingzhu Shao, Chongzhao Wu
Mid-InfraRed spectroscopy is a promising label-free technique that can offer insights into morphological and pathological alterations in biological tissues at the molecular level. Owing to the development of the Fourier...
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Synergistic Interface Engineering of Co(OH)2@AgNPs Heterostructure for Trace Electrochemical Hg2+ Detection

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00123H, Paper
Yanchao Sun, Hongliang Dai, Zheng Wang, Weiqiang Fan, Hongye Bai
The on-site detection of toxic mercury ions (Hg2+) at trace levels is critical for environmental monitoring and compliance with stringent environmental regulations. However, developing electrochemical sensors that simultaneously achieve high...
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Brand discrimination of pet food via near-infrared spectroscopy combined with modified SPA-SI information enhancement

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00372A, Paper
Chengbo Yang, Wanqiang Pan, Song Zhang, Linxi Xu, Haofei Wang, Zhiliang Zhao
For pet food consumers, it is essential to identify authentic brands quickly, simply, and cost-effectively. In this study, 353 pet food samples from four brands were selected, and high-precision brand...
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Species Identification of Animal Glue Adhesives on Polychrome Cultural Heritage: An Integrated Analytical Approach Combining Gel Sampling, ATR-FTIR Spectroscopy, and Machine Learning

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00017G, Technical Note
Xinyu Xie, Wanru Wang, Qin Huang, Wenyuan Zhang, Xinyue Zhu, Xiaoyan Liu, Haixia Zhang
Accurate identification of protein adhesive sources in polychrome relics is critical for their conservation. Conventional infrared spectroscopy faces limitations in cross-species discrimination of such adhesives. To address this, we developed...
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Quantitative determination of maslinic acid and oleanolic acid in olive pomace using high-speed shear extraction and liquid chromatography

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D5AY01925G, Paper
Sheng-Bing Wang, Kun Yang, Dong Pei, Lu-Mei Pu, Xinyi Huang
Olive pomace contains abundant maslinic acid and oleanolic acid, maslinic acid and oleanolic acid are pentacyclic triterpenoid compounds with excellent biological activity. In this study, a method combining high-speed shear...
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