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Genetic analysis with pyrosequencing using loop pipetting and a light dependent resistor

Anal. Methods, 2021, Advance Article
DOI: 10.1039/D1AY01123E, Paper
Faisal Iqbal, Muhammad Imran Shabbir
A DNA sequencer called LoopSeeq was developed using pyrosequencing chemistry where iterative addition of dNTPs was performed by contact dispensing through a loop pipette and detection of chemiluminescence with inexpensive light sensor LDR for point-of-care applications.
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A relative quantitation method for measuring DNA methylation and hydroxymethylation using guanine as an internal standard

Anal. Methods, 2021, 13,4614-4622
DOI: 10.1039/D1AY00897H, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Krisztina Németh, Katalin Mészáros, Borbála Szabó, Henriett Butz, Tamás Arányi, Pál T. Szabó
A relative LC-MS/MS quantitation method for DNA methylation study, where in situ guanine was used as internal standard.
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Development and validation of a multi-residue method for the simultaneous analysis of brominated and organophosphate flame retardants, organochlorine pesticides, and polycyclic aromatic compounds in household dust

Anal. Methods, 2021, 13,4623-4633
DOI: 10.1039/D1AY00860A, Paper
Wenrui Zhang, Yonghui Wang, Meilu Hao, Biao Kong, Peng Liang, Yan Yang, Shengtao Ma
A multi-residue analysis of 20 organochlorine pesticides, 15 polycyclic aromatic hydrocarbons, 8 polybrominated diphenyl ethers, 3 hexabromocyclododecane, 8 synthetic musks , and 7 organophosphate esters in indoor dusts was developed and evaluated.
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Detection of organophosphorus pesticides: exploring oxime as a probe with improved sensitivity by CeO2-modified electrode

Anal. Methods, 2021, 13,4634-4641
DOI: 10.1039/D1AY01235E, Paper
Qiu Sun, Jiyu Du, Li Tian, Jianfeng Wu, Xuelin Zhang
In this work, an oxime-based electrochemical sensor was prepared to achieve a sensitive and convenient determination of non-electroactive OPs by using the catalytic effect of CeO2 toward oxime oxidation.
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Determination of antimalarial drugs in pharmaceutical formulations and human blood by liquid chromatography: a review

Anal. Methods, 2021, 13,4557-4584
DOI: 10.1039/D1AY01173A, Critical Review
Eduarda Alves Penna, Jéssica Cordeiro Queiroz de Souza, Marcone Augusto Leal de Oliveira, Paula Rocha Chellini
The evolution of different analytical methods that have been applied to the determination of antimalarial drugs in pharmaceutical formulations and human blood by liquid chromatography.
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Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the quantification of voriconazole in human cerebrospinal fluid

Anal. Methods, 2021, 13,4585-4593
DOI: 10.1039/D1AY01103K, Paper
Liuhan Dong, Nan Bai, Tianlin Wang, Yun Cai
A simple and accurate method for the determination of voriconazole concentrations in human CSF was developed and validated, which can be used for drug monitoring in the treatment of central nervous system infections.
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Rapid determination of trace Cu2+ by an in-syringe membrane SPE and membrane solid-phase spectral technique

Anal. Methods, 2021, 13,4691-4698
DOI: 10.1039/D1AY01352A, Paper
Long Li, Kehan Xu, Zuohua Huang, Xinxin Xu, Jibran Iqbal, Liang Zhao, Yiping Du
A new in-syringe membrane SPE and solid-phase visible spectral method was proposed for rapid extraction and visible spectral determination of Cu2+. The Cu(DDTC)2 complex can be determined without elution and applied in water and blood plasma samples.
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One-step hydrothermal synthesis of nitrogen-doped carbon dots as a super selective and sensitive probe for sensing metronidazole in multiple samples

Anal. Methods, 2021, 13,4652-4661
DOI: 10.1039/D1AY01009C, Paper
Jinyan Du, Chaofeng Wang, Pingchuan Yuan, Qin Shu, Na Xu, Ying Yang, Shuangqing Qi, Yin Ye, Changqing Zhu
Using fluorescence quenching of N-CDs with bright blue emission, a new sensing nanoplatform was constructed for the successful detection of metronidazole in real samples.
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Metabolomics-based screening analysis of PPCPs in water pretreated with five different SPE columns

Anal. Methods, 2021, 13,4594-4603
DOI: 10.1039/D1AY01313K, Paper
Weifeng Xue, Haiqin Zhang, Mengyao Liu, Xi Chen, Shuwen He, Yingqian Chu
A novel metabolomics-based screening method was developed for the sample pretreatment of PPCPs by SPE columns through seeking ‘biomarkers’.
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Comparison and recent progress of molecular imprinting technology and dummy template molecular imprinting technology

Anal. Methods, 2021, 13,4538-4556
DOI: 10.1039/D1AY01014J, Critical Review
Ru-Nan Chen, Shu-He Kang, Jia Li, Li-Na Lu, Xing-Ping Luo, Lan Wu
Molecular imprinting technology for the preparation of polymers with specific molecular recognition function had become one of the current research hotspots.
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