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Sensitive and reliable Kawasaki disease related microRNA analysis via self-priming chain extension cascades

Anal. Methods, 2026, 18,4898-4906
DOI: 10.1039/D6AY00576D, Paper
Qiuling Huang, Jia Yang
Kawasaki disease (KD) is a leading cause of acquired heart disease in children, requiring timely diagnosis.
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Target-to-signal conversion and spatial enrichment cascade boost CRISPR/Cas12a biosensing for trace-level pathogen detection

Anal. Methods, 2026, 18,4851-4857
DOI: 10.1039/D6AY00441E, Paper
Yu Liu, Xudong Yue, Bowen Li, Haoyu Yang, Yu Wang, Shenguang Ge, Su Liu
A CRISPR/Cas12a-activated DNA nanowire biosensor has been developed for the highly sensitive detection of Salmonella typhimurium.
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Correction: High-performance identification of insulating materials by using generalized spectrum in laser-induced breakdown spectroscopy

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY90069K, Correction
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Junfei Nie, Furong Chen, Ting Luo, Jinke Chen, Jiapei Cao, Qiang Huang, Deng Zhang, Zhenlin Hu
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Robust Pt nanozyme for visual isoniazid determination in commercial tablets and biosamples

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00345A, Paper
Lili Ai, Qi Zhang, Chenwang Zhang, Zhi Xia, Xiaoxu Cao, Yizhou Xu, Phouphien Keoingthong, Shengkai Li
A reliable method for isoniazid (INH) determination is critical for personalized tuberculosis therapy. In this study, we developed a robust colorimetric biosensor using a peroxidase (POD)-like platinum nanozyme (Pt-NZ) as...
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Blue Light Enhances Background Current and Dopamine Sensitivity of Carbon-Fiber Microelectrodes During Fast-Scan Cyclic Voltammetry

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00403B, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.
Eric Daniel Donarski, David Robert Luedeka, B. Jill Venton
Electrochemical measurements of neurotransmitters in tissue are often made in conjunction with optogenetic and fluorescent techniques which expose the electrode to light. Recently, our lab observed that light affects the...
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Advancements in plant-based materials for sustainable biomedical applications

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D5AY02086G, Critical Review
Meenakshi Choudhary, Dharmesh Kumar, Penny P. Govender, Sudheesh K. Shukla
Biosensing technologies play a critical role across the healthcare, environmental monitoring, and food safety sectors.
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Urease-coated polydopamine nanomotors as self-propelled biosensors for non-invasive diagnosis: detection of prostate cancer-associated miR-141 in urine

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00466K, Paper
Open Access Open Access
Creative Commons Licence&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Semanur Özcan Özseven, Gözde Yurdabak Karaca, Lütfi Öksüz, Joseph Wang, Ayşegül Uygun Öksüz
FAM-ssDNA-PDA/PLL@UR nanomotors were fabricated by coating PDA nanobowls with PLL and urease, followed by immobilization of FAM-ssDNA probes. Selective miR-141 detection was achieved through specific hybridization with the functionalized nanomotors.
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Determination of five trace anions in electronic-grade hydrofluoric acid by two-dimensional ion-exclusion/ion-exchange chromatography

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00559D, Paper
Zhou Zheng, Miaogen Chen, Yan Lu, Tao Ye, Xin Shen
A novel 2D-IC strategy utilizes Taylor–Aris dispersion to block suppressor feedback, enabling ultra-trace anion quantification in electronic-grade HF. Integrating a 3.0 m delay tubing into a 2D-IC system completely blocks matrix feedback, achieving ultra-trace anion detection in electronic-grade HF.
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Rapid colorimetric detection of pathogenic bacteria by antibiotic-conjugated gold nanoparticles in a laser-printed µPAD

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00167J, Paper
Adewoyin M. Ogunmolasuyi, Kehinde J. Irhodia, Ayomide J. Olajide, Boluwatife E. Omoniyi, Victoria A. Ogunjobi, Olajide A. Ologunwa
AuNP@antibiotic conjugates for the detection of pathogenic bacteria in a µPAD were developed. µPAD was functionalized with the nanoconjugates, and a color change was observed when the bacterial culture touched the detection zone.
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From Tumors to Neurons: Mass Spectrometry Imaging in Spatial Lipidomics

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00170J, Minireview
Bharath Sampath Kumar
Lipids are fundamental biomolecules that regulate cellular structure, energy metabolism, and signaling, and their dysregulation is increasingly implicated in the pathogenesis of cancer and neurological disorders. Although conventional lipidomics has...
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