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RSM-optimized automated DI-SPME-GC-MS/MS for multi-class trace plasticizers in drinking water

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00322B, Paper

Ying Zhao, Hongfang Gao, Yixin Liu, Wei Wang, Caixia Wang
An RSM-optimized DI-SPME-GC-MS/MS method was developed for the sensitive, precise, and accurate determination of 29 plasticizers (PAEs and NPPs) in drinking water samples.
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A simple method for quantifying microplastics in water utilizing hydrophobic dyes via ultraviolet-visible spectrophotometry

Anal. Methods, 2026, 18,4937-4949
DOI: 10.1039/D6AY00831C, Paper

Yuechuan Luo, Yiping Li, Bangyan Ou, Ruotong Yang, Guoyu Qiao, Zhenggang Wang
A novel method for the microplastics quantitative detection was developed, based on hydrophobic dye staining and spectrophotometry. The staining process exhibited good linear relationship and anti-interference capability.
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Non-enzymatic electrochemical detection of hemoglobin via analyte-triggered in situ phase transformation of β-Ni(OH)2 nanosheets

Anal. Methods, 2026, 18,4907-4916
DOI: 10.1039/D6AY00617E, Paper

Priya Pathmanathan, Harshit Kale, Shourya Singh Thakur, Madhavan Ramasubramani, A. Gomathi
Haemoglobin (Hb) is the principal diagnostic biomarker for anemia, which affects over one billion people globally and poses a critical public health burden in low- and middle-income countries.
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Metal-free miniaturized flexible electrochemical sensors based on nitrogen-doped carbon black for liquid crystal monomer detection

Anal. Methods, 2026, 18,4887-4897
DOI: 10.1039/D6AY00087H, Paper

Xiuying Li, Zhi Li, Zilong He, Fengyu Li
A miniature, portable detection system based on a flexible electrochemical sensor was developed using metal-free nitrogen-doped carbon black for field detection of liquid crystal monomers.
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A two-stage signal enhancement method integrating the Gaussian mixture model and adaptive rolling ball technique for ultrasensitive fluorescent immunochromatographic detection

Anal. Methods, 2026, 18,4805-4818
DOI: 10.1039/D6AY00496B, Paper

Qian Bian, Chongwen Wang, Wenlong Bai, Liping Dai, Tao Zhang, Qian Wang, Long Zhang, Shuai Zheng, Shu Wang
A portable fluorescence detector with GMM-ARB two-stage enhancement achieves ultrasensitive pathogen detection.
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Hexafluoroisopropanol-induced salt-free catanionic surfactant supramolecular solvent for direct immersion single-drop microextraction of sulfonamides and fluoroquinolones in water samples

Anal. Methods, 2026, 18,4866-4875
DOI: 10.1039/D6AY00449K, Paper

Keke Huang, Jia Chen, Wending Yao, Xiao Li
A homemade DI-SDME holder stabilizes high-density HFIP-induced salt-free catanionic surfactant SUPRAS droplets, enabling simple, sensitive and green trace analysis of sulfonamides and fluoroquinolones in water samples.
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Integration of paper-based DNA extraction with digitized image analysis for colorimetric LAMP-based V. parahaemolyticus detection

Anal. Methods, 2026, 18,4927-4936
DOI: 10.1039/D6AY00702C, Paper

Thi Ngoc Diep Trinh, Nguyen Tran Truc Phuong, Kien Cuong Tran, Kieu The Loan Trinh, Hanh An Nguyen
A novel approach integrating paper-based DNA extraction with digitized image analysis – assisted colorimetric LAMP was developed for colorimetric detection of Vibrio parahaemolyticus.
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An exonuclease III-assisted CHA dual-cycle amplification strategy for quencher-free fluorescent detection of miRNA

Anal. Methods, 2026, 18,4917-4926
DOI: 10.1039/D6AY00629A, Paper

Shi-Qian Liao, Jia-Hao Liu, Xin-Yue Liu, Yi-Ting Liu, Chun-Guang Yang, Zhang-Run Xu
A simple, sensitive, and quencher-free fluorescent method for miRNA detection by combining catalytic hairpin assembly (CHA) with exonuclease III (Exo III)-assisted signal amplification.
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Reaction-induced fluorogenic sensing of benzodiazepines: a 3D-printed smartphone-based device with multivariate RGB optimization

Anal. Methods, 2026, 18,4839-4850
DOI: 10.1039/D6AY00325G, Paper

Thiago Alvares Zamaro de Freitas, Matheus Martins Guedes, Camilla Fonseca Silva, Marcella Matos Cordeiro Borges, Álvaro Cunha Neto, Josefredo Rodriguez Pliego, Cleocir José Dalmaschio, Keyller Bastos Borges
A portable 3D-printed smartphone fluorimetric platform enables benzodiazepine detection with multivariate RGB optimization (MLR: R² = 0.9998), achieving laboratory-grade analytical performance with field-deployable simplicity.
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A pathogen-activated DNAzyme triggers hybridization chain reaction for ultra-sensitive salivary detection of Helicobacter pylori

Anal. Methods, 2026, 18,4795-4804
DOI: 10.1039/D6AY00648E, Paper

Qiming Chen, Quanling Dong, Zhengrong Lu, Zhanmin Liu
Helicobacter pylori infection is a major etiological factor in chronic gastritis, peptic ulcer disease, and gastric cancer, highlighting the demand for sensitive, non-invasive, and operationally simple diagnostic strategies.
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