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Application of surface-enhanced Raman spectroscopy in the diagnosis of infectious diseases

Anal. Methods, 2026, 18,4533-4546
DOI: 10.1039/D6AY00691D, Minireview

Lili Tian, Yanxi Li, Tao Wang, Jie Gong, Junbo Han, Jingdong Yuan, Jin Chen, Huiping Zhang, Lihua Qian
Surface-enhanced Raman spectroscopy (SERS) is increasingly emerging as a pivotal analytical technique in the field of clinical diagnostics.
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Recent advances in microfluidic technologies for circulating tumor cell isolation: from separation strategies to clinical translation

Anal. Methods, 2026, 18,4547-4574
DOI: 10.1039/D6AY00687F, Critical Review

Chentao Li, Jialuo Cheng, Dingfu Zhao, Rui Cao, Yinglin Wang, Siyuan Zhao, Dezhi Li, Qing Liu
Microfluidic technologies isolate rare circulating tumor cells through physical, affinity-based and surface-engineered strategies, enabling downstream molecular analysis and clinical translation.
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Smart dual-wavelength UV-vis spectroscopic method and smartphone-based RGB method for the rapid quantification of pyronaridine tetraphosphate: integration with the SDG approach

Anal. Methods, 2026, 18,4712-4722
DOI: 10.1039/D6AY00052E, Paper

Jenish H. Parekh, Abhishek Munjapara, Bhavesh N. Socha, Subrata Patra, Hetal Jebaliya
This study demonstrates the quantification of pyronaridine tetraphosphate using UV-Vis spectroscopy and a smartphone-based method with the integration of an SDG approach.
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A nitrogen-doped carbon dot fluorescent probe for sensitive detection of metronidazole in pharmaceutical samples and evaluation of its cytotoxicity and cell imaging performance

Anal. Methods, 2026, 18,4679-4690
DOI: 10.1039/D6AY00354K, Paper

Jiahui Li, Jingui Zhong, Hanyan Wei, Hongyan Bai
Metronidazole (MTZ) is a widely used nitroimidazole antibiotic, and its excessive use may pose health risks.
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Iodine-starch reaction renewed: determination of iodate in table salts via the lab-in-syringe technique

Anal. Methods, 2026, 18,4645-4654
DOI: 10.1039/D6AY00438E, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Cemre Yıldız, Ivana H. Šrámková, Sercan Yıldırım, Petr Solich, Burkhard Horstkotte
A novel in-syringe automated method was developed for simple, sensitive, and green determination of iodate in table salts.
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Sensitive detection and prostate cancer cellular evaluation of sarcosine via a fluorescence turn-on assay using an N-CQDs/Ag+ nanosensor

Anal. Methods, 2026, 18,4634-4644
DOI: 10.1039/D6AY00357E, Paper

Xinyu Shen, Suli He, Lezhong Qi, Xiayong Jing, Xinqiang Gan, Xingjun He
Sarcosine, a key oncometabolite in prostate cancer (PCa), has emerged as a promising biomarker for disease diagnosis and progression monitoring.
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Recovery of TNT from post-blast soil samples: effects of soil type, extraction methodology, and storage conditions

Anal. Methods, 2026, 18,4589-4598
DOI: 10.1039/D6AY00563B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

A. J. Hecker, H. Upadhyaya, J. V. Goodpaster
Traditionally, determination of explosives and their decomposition products in soil samples involves a 24-hour ultrasonic solid–liquid extraction (SLE) using acetonitrile followed by a “salting out” liquid–liquid extraction (LLE).
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Preparation of nanoflower-based loaded dual nanozymes and their application in colorimetric detection of uric acid in urine

Anal. Methods, 2026, 18,4599-4612
DOI: 10.1039/D6AY00505E, Paper

Junping Yang, Ziyu Song, Lu Huang, Ke Wen, Yuan Lu, Qian Liu
A one-pot bio-inspired synthesis approach was employed to fabricate five types of uricase nanoflowers (UOx-NFs), from which Mn-UOx-NFs with the highest catalytic activity were selected.
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A polymer-integrated flexible gold nanotriangle array for quantitative and nondestructive SERS detection of thiram on apples

Anal. Methods, 2026, 18,4723-4732
DOI: 10.1039/D6AY00537C, Paper

Ze-Bo Zheng, Xiao-Hui Sun, Wan-Hui Guo, Wen Pan, Fan-Li Zhang, Sheng-Hong Liu
Polymer-integrated flexible SERS platform for nondestructive detection on non-planar food surfaces.
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Screening of aggregation properties of cyclic peptides by protein nanopores

Anal. Methods, 2026, 18,4575-4583
DOI: 10.1039/D6AY00427J, Communication

Hang Yang, Wenqi Lu, Dongdong Wang, Xiaoyu Zhang, Zan Li, Minmin Li, Haijuan Qin, Jiaqi Li, Guangyan Qing
Nanopore sensing explores the aggregation behaviors of cyclic peptides, unveiling distinct ionic current signatures and insights into their structural dynamics.
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