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Analytical characterization of bulk R-Salt and its odor profile to establish a framework for canine detection

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00077K, Paper

Janet Crespo-Cajigas, Melissa J. Clinard, Shawanda Roberts, Dawn M. Mills
TD-GC-MS was used to characterize the headspace of an improvised explosive, R-Salt. This study provides foundational data and methodology that is essential for the development and validation of canine training aids and field vapor sampling devices.
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Integration of a Screening-Guided Near-Infrared Aptasensor into a Portable Platform for Quantitative On-Site Detection of N¹-Methyladenosine

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00228E, Paper

Qi Pang, Dandan Zhang, Ruilin Ma, Wuduo Zhao, Xinyue Cao, Zhongyang Huang, Tuanjie Huang, Jiaheng Zhang
N¹-Methyladenosine (m¹A) is an important RNA modification associated with diverse biological processes and disease states, yet rapid and quantitative on-site detection of m¹A remains challenging. Herein, we report a near-infrared...
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Enzyme-free and product-accelerated DNA walker cascade for ultrasensitive detection of tic disorder-associated microRNA

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00424E, Paper

Wei Li, Xiaobin Dou
Tic disorders (TDs) are prevalent neuropsychiatric conditions in children, yet early diagnosis remains challenging due to limited availability and high sequence homology of associated microRNA biomarkers.
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Development and Prospects of Fluorescence Polarization Immunoassay for Pesticide Detection in Food and Environment

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00409A, Critical Review

Weiguo Yu, Zhenjiang Liu
The excessive and improper application of pesticides severely jeopardizes ecological balance and poses a serious threat to human health. Fluorescence polarization immunoassay (FPIA) is a homogeneous immunoassay technique that offers...
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Digital image method based on smartphone assisted by hydrophobic natural deep eutectic solvent for Iron quantification in dietary supplements

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00456C, Paper

Gabriel Bercley De Lima Vitorino, Jackson Rodrigo dos Santos Silva, Vinicius Alcantara carvalho, João Paulo de Almeida, Willian Toito Suarez, Severino Carlos Bezerra de Oliveira, Vagner Bezerra dos Santos
Quality control in dietary supplements is necessary to ensure its safety and effectiveness due to its wide consumption. Conventional methods often include the use of toxic solvents, complex, high power...
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Quantification of microplastics in soil and sediments using dry ice assisted fractionation with an Agilent 8700 laser direct infrared chemical imaging system

Anal. Methods, 2026, 18,3029-3044
DOI: 10.1039/D5AY01753J, Paper

Subharthe Samandra, Jaye Marchiandi, Wesam S. Alwan, Amanda V. Ellis, Bradley O. Clarke
This study reports a novel protocol for the extraction and quantification of 14 different polymers in soil and sediments.
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Construction and application of a coumarin-based fluorescent probe for hypochlorous acid

Anal. Methods, 2026, 18,3018-3028
DOI: 10.1039/D5AY02143J, Paper

Yue Li, Yan Dong, Yingqian Xu, Junyi Hu, Jiaoyue Zhang, Ying Chen, Dengbin Wu
XDS acts as a fluorescent probe for HClO recognition. It has been successfully applied to the semi-quantitative detection of HClO in real water samples, as well as bioimaging of HClO in HepG2 cells and zebrafish.
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A novel NIR fluorescent probe based on p-mercaptophenylboronic acid-functionalized copper nanoclusters for capmatinib quantification

Anal. Methods, 2026, 18,2981-2990
DOI: 10.1039/D5AY01825K, Paper

Ali O. Alqarni, Rayed Ali A. Alqahtani, Ashraf M. Mahmoud, Yahya S. Alqahtani, Bassam S. M. Al Kazman, Fatmah M. Alshareef, Mohamed N. Goda, Laila S. Alqarni, Ramadan Ali, Al-Montaser Bellah H. Ali, Mohamed M. El-Wekil
A red-emitting p-MPBA@CuNC “turn-off” fluorescent probe was developed for highly sensitive and selective capmatinib detection.
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Oxygen concentration measurement in 3D cell culture using multifocal optical projection microscopy

Anal. Methods, 2026, 18,2970-2980
DOI: 10.1039/D5AY01921D, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Birhanu Belay, Mart Kroon, Kaisla Walls, Minna Kellomäki, Jari Hyttinen
Fluorescent intensity-based oxygen concentration measurement in large-volume 3D cell cultures using microsensor beads and multifocal optical projection microscopy.
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High-throughput colorimetric LAMP detection of Mycoplasma gallisepticum with intelligent algorithm-assisted analysis

Anal. Methods, 2026, 18,2951-2959
DOI: 10.1039/D6AY00198J, Paper

Wuyang Jing, Qianyi Cai, Yucen Liang, Renhang Xiao, Qijie Lin, Xiaozhen Xu, Ruidong Liu, Chenggang Xu, Hongchao Gou, Haiyan Shen, Ming Liao, Jianmin Zhang
A colorimetric LAMP assay using cresol red enables visual detection of Mycoplasma gallisepticum, while an intelligent smartphone application (Lab Color Analyzer) automates analysis of up to 64 samples, achieving 98% concordance with qPCR.
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