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A CHEF-driven fluorescent turn-on probe for sensitive and rapid Al3+ detection in live MDA-MB-231 cells

Anal. Methods, 2026, 18,4858-4865
DOI: 10.1039/D6AY00264A, Paper

Rahul Naskar, Gita Rani Murmu, Subrata Mandal, Rimi Mukherjee, Arpan Halder, Amitav Biswas, Moumita Ghosh, Saswati Gharami, Nabendu Murmu, Tapan K. Mondal
A novel fluorescent switch (PIMB) has been fabricated through a straightforward Schiff base reaction and exhibits highly selective sensing of Al³⁺ over other metal ions at physiological pH.
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Determination of short-chain chlorinated paraffins in carpets by gas chromatography-electron capture negative ionization mass spectrometry

Anal. Methods, 2026, 18,4950-4957
DOI: 10.1039/D6AY00647G, Paper

Ting Gu, Yongli Wu, Lianrui Mei, Yu Zhang, Yi Han
A method based on GC-ECNI-MS was developed for determining short-chain chlorinated paraffins (SCCPs) in carpets, offering data support for global risk control of SCCPs use in carpet products.
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Sweat-based electrochemical wearable biosensors for sports performance and fatigue monitoring: from laboratory prototypes to field deployment

Anal. Methods, 2026, 18,4753-4785
DOI: 10.1039/D6AY00459H, Tutorial Review

Umapathi Krishnamoorthy
Emerging sweat-based wearable biosensors offer non-invasive, continuous assessment of athlete performance, with innovations in sensing, data analytics, and system integration enabling practical deployment beyond laboratory settings.
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Development of a bioluminescent enzyme immunoassay for glycocholic acid based on a single-chain variable fragment-nanoluciferase fusion

Anal. Methods, 2026, 18,4819-4825
DOI: 10.1039/D6AY00731G, Paper

Yunping Mu, Huajian Cai, Xindan Zhang, Mingxia Lin, Junhao Zeng, Yiyun Wang, Ziming Wu, Suqing Zhao, Xiping Cui
As glycocholic acid (GCA) has been recognized as a biomarker for hepatocellular carcinoma (HCC), its detection is crucial for the prevention, diagnosis, and treatment of HCC.
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Stabilization of a ring-opened rhodamine probe via multi-noncovalent interactions for the dual-mode detection of nitazenes

Anal. Methods, 2026, 18,4876-4886
DOI: 10.1039/D6AY00429F, Paper

Yujie Feng, Yudong Li, Bingbing Zhao, Chuanfang Zhao, Jingxiang Li, Luyan Yang, Baiyi Zu, Xincun Dou
Nitazene opioids, representing a potent class of emerging synthetic substances, have emerged as a significant threat to public health and biosafety worldwide.
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Rational design of L-histidine-stabilized fluorescent copper nanoclusters for highly selective and sensitive detection of sunset yellow

Anal. Methods, 2026, 18,4826-4838
DOI: 10.1039/D6AY00800C, Paper

Xingwu Li, Xiaotian Liu, Lili Yuan, Zhengshan Tian
The water-soluble, blue-green fluorescent copper nanoclusters demonstrate exceptional stability in high-temperature and high-salt environments, overcoming the limitations of many fluorescent probes in complex matrices.
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Pheromone measurement using secondary electrospray ionization and portable membrane inlet mass spectrometry

Anal. Methods, 2026, 18,4786-4794
DOI: 10.1039/D6AY00269B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Stamatios Giannoukos, Dimitris Raptopoulos, Maria Konstantopoulou
A secondary electrospray ionization high-resolution mass spectrometry system and a portable membrane inlet mass spectrometer have been used for the first time to detect and monitor insect sex pheromones, both qualitatively and quantitatively.
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Sensitive and reliable Kawasaki disease related microRNA analysis via self-priming chain extension cascades

Anal. Methods, 2026, 18,4898-4906
DOI: 10.1039/D6AY00576D, Paper

Qiuling Huang, Jia Yang
Kawasaki disease (KD) is a leading cause of acquired heart disease in children, requiring timely diagnosis.
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Target-to-signal conversion and spatial enrichment cascade boost CRISPR/Cas12a biosensing for trace-level pathogen detection

Anal. Methods, 2026, 18,4851-4857
DOI: 10.1039/D6AY00441E, Paper

Yu Liu, Xudong Yue, Bowen Li, Haoyu Yang, Yu Wang, Shenguang Ge, Su Liu
A CRISPR/Cas12a-activated DNA nanowire biosensor has been developed for the highly sensitive detection of Salmonella typhimurium.
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Blue Light Enhances Background Current and Dopamine Sensitivity of Carbon-Fiber Microelectrodes During Fast-Scan Cyclic Voltammetry

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00403B, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Eric Daniel Donarski, David Robert Luedeka, B. Jill Venton
Electrochemical measurements of neurotransmitters in tissue are often made in conjunction with optogenetic and fluorescent techniques which expose the electrode to light. Recently, our lab observed that light affects the...
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