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Enhanced protein binding to off-stoichiometry thiol–ene microfluidic devices: a novel linker approach

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01384D, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Rihards Ruska, Edmunds Zutis, Kaspars Tars, Andris Kazaks, Gunita Paidere, Janis Cipa, Igor Vozny, Toms Freimanis, Maira Elksne, Anatolijs Sarakovskis, Raivis Zalubovskis, Andris Anspoks
Protein binding efficiency to OSTE increased by approximately 4 orders of magnitude using a novel linker. This linker provides a shelf-stable and simple method for protein attachment to OSTE surfaces.
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A novel method for visual microarray detection of antibiotic resistance genes

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D5AY01830G, Paper

Shenglong Ma, Baowei Zhao, Yunxia Li, Hui Liu, Rui Zhang
This study presents a novel, portable method for detecting ARGs using a microarray platform with a centrifuge-free concentration device and dual probe amplification combined with silver staining for sensitive, on-site detection.
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Analytical performance and calibration strategies of low-cost particulate matter sensors for indoor and workplace monitoring—a review

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01554E, Critical Review

Zikang Feng, Lina Zheng, Dou Liu
This review summarizes current evidence on low-cost particulate matter (PM) sensors for indoor and occupational environments and proposes a framework that links performance evaluation, calibration, and uncertainty to decision-making.
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Development of colloidal gold labeled dual-probe lateral flow immunoassay for sensitive aflatoxin B1 detection by signal amplification strategy

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY01543J, Paper

Lingling Wang, Lingzhi Yan, Haoran Wang, Rui Liu, Ying Fan, Yuan-Lin Sun
Lateral flow immunoassay (LFIA), performed with easy operation and short analysis time, is widely favored by many researchers. However, traditional LFIA with insufficient sensitivity hinders its broader applications. Here, a...
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LEC-former: enhancing functional group identification in FTIR spectra by improving weak peak perception

Anal. Methods, 2025, Advance Article
DOI: 10.1039/D5AY01519G, Paper

ShiDi Xie, LiJuan Peng, JunNa Zhang, YiLong Kang, HongCheng Zhou, ZongJun Ren
A transformer-based model with a local enhancement coupling module enables robust learning of vibrational patterns for functional group identification in infrared spectra.
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Electrochemical Determination of Dopamine using Flowers-Derived Carbon Quantum Dots/Polydopamine Composite Film Modified Electrode

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY01457C, Paper

Tanu Patel, Surendar Balu, Dhanraj Ganapathy, Ashok Kumar Sundramoorthy
Carbon quantum dots (CQDs) are attracting interest as innovative nanomaterials for electrochemical sensing, owing to their robust photoluminescence, adjustable surface properties, and advantageous charge-transfer characteristics. This study presents a sustainable...
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Luminescent Metal–Organic Framework (MOF) sensor for sensitive determination of nicotine in breast milk

Anal. Methods, 2025, Accepted Manuscript
DOI: 10.1039/D5AY01777G, Paper

Paola A Avaca Gagliardi, German Gómez, Liliana P Fernández, Carolina Talio
Breastfeeding is essential for the healthy development and growth of infants, fostering a strong bond between mother and child. Exposure to nicotine through maternal smoking represents a significant risk to...
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Correction: Circulating tumour DNA methylation: unlocking a new chapter in cancer diagnosis and treatment

Anal. Methods, 2025, 17,9689-9689
DOI: 10.1039/D5AY90155C, Correction

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Xingtong Zhan, Zhuo Jin, Shuhui Yang, Siqi Sun, Liying Zhang, Xinchen Zhou, Zhuo Zhang, Shuhan Dong, Yan Jiang, Limei Liu
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Development of an HPV 16 rapid test founded in user-centered design with primary care clinicians

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D5AY01621E, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Luke P. Brennan, Francesca Hamacher, Layla A. Claure, Ana L. Claure Dips, Sathveka Sembian, Lara N. Balian, Andrew D. Piepho, Aaron C. Ermel, Jacqueline C. Linnes, Natalia M. Rodriguez
Clinician-informed nucleic acid test for cervical cancer screening to facilitate same-visit results to improve follow-up care.
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Electrochemical aptamer-based sensor for cerebrospinal fluid detection

Anal. Methods, 2025, 17,9649-9658
DOI: 10.1039/D5AY01335F, Paper

Xinlei Chen, Mehmet Senel, Junye Li, Arash Abiri, Andrej Lupták, Frank P. K. Hsu, Edward C. Kuan, Michelle Khine
We developed a new class of E-AB biosensors capable of detecting target analytes even in the absence of complete biomarker identification and outlined essential optimization strategies to enhance signal suppression performance.
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